硼酸及其衍生物在荧光分子开关中的应用

荧光分子开关中主体和客体之间可以通过多种方式相结合,其中带有荧光团的硼酸衍生
物与糖或羟基化合物的结合是通过共价键形成的。糖化学在生命科学中起着非常重要的作用,因此对糖的识别和检测在医学、细胞生物学等领域具有至关重要的意义。硼酸衍生物可以作为荧光分子开关对糖进行有效的选择性识别,因而受到科学家们的广泛关注。本文对近年来国内外相关研究成果进行了综述。
关键词　硼酸衍生物　荧光　开关　传感器　糖
Abstract 　There are many types of combinations between the hosts and guests in fluorescent molecular switch. Among them , boric acid derivatives with fluorophore may selectively recognize saccharides or hydroxyl compounds through the formation of covalent bond. Since the chemistry of saccharides plays a significant role in life science , the recognition and detection of saccharides are very important in medicine , cellular , biological science and other fields. As a sort of efficient fluroescent molecular sensors , the boric acid derivatives are sensitive and selective in the recogni2 tion of some saccharides and have attracted extensive attentions of many chemists. In this context , the relative results of research about this type of fluroescent molecular switches in recent years were reviewed.
Key words 　Boric acid , Fluorescence , Switch , Sensor , Saccharide